The 17-year-old Izumi Shinichi lives with his mother and father in a quiet neighborhood in Tokyo. One night, worm-like aliens called Parasytes invade Earth, taking over the brains of human hosts by entering through their ears or noses. One Parasyte attempts to crawl into Shinichi's ear while he sleeps, but fails since he is wearing headphones, and enters his body by burrowing into his arm instead, taking over his right hand and is named Migi.

Danna ga Nani wo Itteiru ka Wakaranai Ken also known as 'I Can't Understand What My Husband Is Saying' in english title, revolves around the daily life of an earnest, hardworking office lady named Kaoru and her otaku husband, Hajime, who is totally immersed in a certain huge net bulletin board system.

Umio is a shy kid who just started his part time job at a manga store smack dab in the middle of the city. But his lifestyle isn't as glamorous as the neon lights that illuminate the city.